People keep saying video game adaptations never do well and therefore never will, which is reductive. That's only the case because in the past they've either been complete shit, had horrendous marketing, or they came long after the game had already become irrelevant. The original Mortal Kombat is the outlier with a 70mil gross in 1995, decent quality compared to other adaptations, and it was released when the games were still all the buzz.
The Resident Evil franchise has been mostly successful, and would probably be even more successful if they focused more on horror instead of shitty outdated wire-fu/bullet-time action sequences or if the games were still relevant. Not to mention if they were any good.
The majority of video game adaptations have flopped or failed to break out not because audiences have something against them, it's because the movies sucked.