For lead actors:
Best Actor
Leonardo DiCaprio, The Revenant
Jake Gyllenhaal, Southpaw
Josh Brolin, Hail, Caesar!
Matt Damon, The Martian
Matthew McConaughey, Sea of Trees
Joaquin Phoenix might also sneak in for the new Woody Allen. Bradley Cooper in Joy is a supporting role. I predict an obvious win for DiCaprio.
Best Actress
Meryl Streep, Ricki and the Flash
Julianne Moore, Freeheld
Cate Blanchett, Carol
Carey Mulligan, Suffragette
Jennifer Lawrence, Joy
While Nicole Kidman could sneak in for Queen of the Desert, something tells me this could go the way of Grace of Monaco. Another possibility is Emma Stone for the new Woody Allen, but she will have to really impress I think. Mulligan is leading Suffragette, not Streep - she is just a cameo.
The obvious for supporting actors: Tom Hardy (The Revenant) and Rooney Mara (Carol). I am also wondering about Rachel McAdams as a potential supporting nominee for Spotlight. It's going to be an interesting film regardless. You've also got Michael Keaton in there, who will likely win this year. And Adam Driver for Silence seems like a possible bet for supporting as well.