Deadpool will be treated as a big comedy, but still small in the face of everything else.
BVS, Civil War, Xmen are major.
Suicide Squad has enough to differentiate itself, that could be true for Strange but we don't know yet.
Gambit and Dr Strange will do well but not be huge major movies. Something on the scale of AntMan. Strange will probably gross more.
I still beleive in the theory that 2Pac was killed in an assassination paid for by Will Smith.
Will knew Pac was too close to Jada and decided to get rid of him.