Well, it is a 4-day opening, as opposed to ST09's 3-day opening,
it is a sequel, so it is naturally more frontloaded,
and it faces FF6, TH3 + Epic next weekend, which also means a smaller screen count, in addition to more competition.
Will it have legs better than Indy 4? Definitely.
Will it have a 2.75+ multiplier? Highly doubt it.
From the 4-day? Indiana Jones 4 had a 2.5 multiplier for comparison, and the amount of competition is insane in the next few weeks. I think that a 2.75 multiplier is the very maximum it can get, and even that's very generous.