I'm not sure about that. It's a mixed bag in some ways.
On the negative side: The last time Hollywood put out a movie with Oppenheimer as a main character, it bombed hard in 1989 with a $30 million budget and less than $4 million of total box office. That $30 million budget in 1989 was pretty damn big. Burton's 1989 Batman film had a $40 million production budget for perspective. The 1989 Oppy film had Paul Newman in the Matt Damon role of General Leslie Groves. Paul Newman won Best Actor at the Oscars for The Color of Money in March of 1987. So his name brand in the late 1980's was about as hot as you can get, and the Oppy film still bombed really bad. Knowing these facts about what happened with the 1989 movie, it seems like a pretty big risk by Universal to spend $100 million on production & another $100 million on marketing the new Oppy film.
On the positive side: Nolan obviously gained a lot of credibility and brand power with his earlier films in the 2 decades leading up to the release of his Oppy film last year. The film accidentally ended up with a perfect release date, thanks to all of the Barbie hype on the same opening weekend. Oppy did not have the full screen count Nolan probably hoped to have, but a pretty decent chunk of the Barbie audience decided to also check out the Oppy film. That's a pretty unexpected boost for Oppy's box office from the Barbie fans. Another accidental element that helped Oppy's box office is Vlad Putin constantly threatening to launch nukes at Western countries. This could have created a negative effect in the sense that people would rather bury their heads in the sand instead of watching a movie about such a serious subject matter. But maybe this type of nuclear fear-mongering in real life actually gave the movie some kind of extra boost at the box office.