Well, Di Caprio won for dumber reasons and the competition this year isn't much better. They'll give it to him for his career if nothing else. Chalamet pulling an Adrien Brody, or DDL delivering such an all-timer of a performance that they can't help but reward him again are both fun possibilities but pretty unlikely. Other people's chances are even smaller.
For now I pretty much just hope to see Dafoe, James Ivory and Deakins win theirs. Don't have horses in any other races.