Well Bob Iger said Deadpool can remain R Rated at Disney. They're not dumb enough to neuter part of the appeal of Deadpool which is the R Rating. I think what will happen first is MCU characters will make appearances in Deadpool films before the other way around happens.
"It [Deadpool] clearly has been and will be Marvel branded. But we think there might be an opportunity for a Marvel-R brand for something like Deadpool," said Iger. "As long as we let the audiences know what's coming, we think we can manage that fine."